Extracellular NLRP3 inflammasome particles are internalized by human coronary artery smooth muscle cells and induce pro-atherogenic effects

Inflammation driven by intracellular activation of the NLRP3 inflammasome is involved in the pathogenesis of a variety of diseases including vascular pathologies. Inflammasome specks are released into the extracellular compartment from disrupting pyroptotic cells. The potential uptake and function o...

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Detalles Bibliográficos
Autores principales: Gaul, Susanne, Schaeffer, Karen Marie, Opitz, Lena, Maeder, Christina, Kogel, Alexander, Uhlmann, Luisa, Kalwa, Hermann, Wagner, Ulf, Haas, Jan, Behzadi, Amirhossein, Pelegrin, Pablo, Boeckel, Jes-Niels, Laufs, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313534/
https://www.ncbi.nlm.nih.gov/pubmed/34312415
http://dx.doi.org/10.1038/s41598-021-94314-1

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