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ChAdOx1 nCoV-19 protection against SARS-CoV-2 in rhesus macaque and ferret challenge models

Vaccines against SARS-CoV-2 are urgently required, but early development of vaccines against SARS-CoV-1 resulted in enhanced disease after vaccination. Careful assessment of this phenomena is warranted for vaccine development against SARS CoV-2. Here we report detailed immune profiling after ChAdOx1...

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Detalles Bibliográficos
Autores principales: Lambe, Teresa, Spencer, Alexandra J., Thomas, Kelly M., Gooch, Karen E., Thomas, Stephen, White, Andrew D., Humphries, Holly E., Wright, Daniel, Belij-Rammerstorfer, Sandra, Thakur, Nazia, Conceicao, Carina, Watson, Robert, Alden, Leonie, Allen, Lauren, Aram, Marilyn, Bewley, Kevin R., Brunt, Emily, Brown, Phillip, Cavell, Breeze E., Cobb, Rebecca, Fotheringham, Susan A., Gilbride, Ciaran, Harris, Debbie J., Ho, Catherine M. K., Hunter, Laura, Kennard, Chelsea L., Leung, Stephanie, Lucas, Vanessa, Ngabo, Didier, Ryan, Kathryn A., Sharpe, Hannah, Sarfas, Charlotte, Sibley, Laura, Slack, Gillian S., Ulaszewska, Marta, Wand, Nadina, Wiblin, Nathan R., Gleeson, Fergus V., Bailey, Dalan, Sharpe, Sally, Charlton, Sue, Salguero, Francisco J., Carroll, Miles W., Gilbert, Sarah C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313674/
https://www.ncbi.nlm.nih.gov/pubmed/34312487
http://dx.doi.org/10.1038/s42003-021-02443-0