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BH3-only protein expression determines hepatocellular carcinoma response to sorafenib-based treatment
Hepatocellular carcinoma (HCC) represents a global health challenge with limited therapeutic options. Anti-angiogenic immune checkpoint inhibitor-based combination therapy has been introduced for progressed HCC, but improves survival only in a subset of HCC patients. Tyrosine-kinase inhibitors (TKI)...
Autores principales: | Busche, Stephanie, John, Katharina, Wandrer, Franziska, Vondran, Florian W. R., Lehmann, Ulrich, Wedemeyer, Heiner, Essmann, Frank, Schulze-Osthoff, Klaus, Bantel, Heike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313681/ https://www.ncbi.nlm.nih.gov/pubmed/34312366 http://dx.doi.org/10.1038/s41419-021-04020-z |
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