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A modified age-structured SIR model for COVID-19 type viruses

We present a modified age-structured SIR model based on known patterns of social contact and distancing measures within Washington, USA. We find that population age-distribution has a significant effect on disease spread and mortality rate, and contribute to the efficacy of age-specific contact and...

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Detalles Bibliográficos
Autores principales: Ram, Vishaal, Schaposnik, Laura P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313685/
https://www.ncbi.nlm.nih.gov/pubmed/34312473
http://dx.doi.org/10.1038/s41598-021-94609-3
Descripción
Sumario:We present a modified age-structured SIR model based on known patterns of social contact and distancing measures within Washington, USA. We find that population age-distribution has a significant effect on disease spread and mortality rate, and contribute to the efficacy of age-specific contact and treatment measures. We consider the effect of relaxing restrictions across less vulnerable age-brackets, comparing results across selected groups of varying population parameters. Moreover, we analyze the mitigating effects of vaccinations and examine the effectiveness of age-targeted distributions. Lastly, we explore how our model can applied to other states to reflect social-distancing policy based on different parameters and metrics.