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Population Pharmacokinetics of High-Dose Methotrexate in Chinese Pediatric Patients With Acute Lymphoblastic Leukemia

High-dose methotrexate (HD-MTX) is widely used in pediatric acute lymphoblastic leukemia (ALL) treatment regimens. In this study, we aimed to develop a population pharmacokinetic (PK) model of HD-MTX in Chinese pediatric patients with ALL for designing personalized dosage regimens. In total, 4,517 M...

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Detalles Bibliográficos
Autores principales:	Gao, Xuan, Qian, Xiao-Wen, Zhu, Xiao-Hua, Yu, Yi, Miao, Hui, Meng, Jian-Hua, Jiang, Jun-Ye, Wang, Hong-Sheng, Zhai, Xiao-Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313761/ https://www.ncbi.nlm.nih.gov/pubmed/34326772 http://dx.doi.org/10.3389/fphar.2021.701452

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