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Cytoprotection of rat hepatocytes by desipramine in a model of simulated ischemia/reperfusion
We investigated the cytoprotective effect of desipramine (DMI) during in vitro simulated ischemia/reperfusion (I/R) of rat hepatocytes. Primary hepatocytes isolated from male Sprague-Dawley rats were subjected to 4 h of anoxia at pH 6.2 followed by normoxia at pH 7.4 for 2 h to simulate ischemia and...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313843/ https://www.ncbi.nlm.nih.gov/pubmed/34337165 http://dx.doi.org/10.1016/j.bbrep.2021.101075 |