Human Hyaluronidase PH20 Potentiates the Antitumor Activities of Mesothelin-Specific CAR-T Cells Against Gastric Cancer

T cell infiltration into tumors is essential for successful immunotherapy against solid tumors. Herein, we found that the expression of hyaluronic acid synthases (HAS) was negatively correlated with patient survival in multiple types of solid tumors including gastric cancer. HA impeded in vitro anti...

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Detalles Bibliográficos
Autores principales: Zhao, Ruocong, Cui, Yuanbin, Zheng, Yongfang, Li, Shanglin, Lv, Jiang, Wu, Qiting, Long, Youguo, Wang, Suna, Yao, Yao, Wei, Wei, Yang, Jie, Wang, Bin-Chao, Zhang, Zhenfeng, Zeng, Hui, Li, Yangqiu, Li, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313856/
https://www.ncbi.nlm.nih.gov/pubmed/34326835
http://dx.doi.org/10.3389/fimmu.2021.660488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313856/
https://www.ncbi.nlm.nih.gov/pubmed/34326835
http://dx.doi.org/10.3389/fimmu.2021.660488

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