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N6-methyladenosine methyltransferases: functions, regulation, and clinical potential
N6-methyladenosine (m6A) has emerged as an abundant modification throughout the transcriptome with widespread functions in protein-coding and noncoding RNAs. It affects the fates of modified RNAs, including their stability, splicing, and/or translation, and thus plays important roles in posttranscri...
Autores principales: | Huang, Wei, Chen, Tian-Qi, Fang, Ke, Zeng, Zhan-Cheng, Ye, Hua, Chen, Yue-Qin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313886/ https://www.ncbi.nlm.nih.gov/pubmed/34315512 http://dx.doi.org/10.1186/s13045-021-01129-8 |
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