Complete Response for Advanced Hepatocellular Carcinoma by Conversion Surgery Therapy Following a Good Response of Regorafenib Despite Rapid Progressive Disease with Sorafenib

A 68-year-old man with hepatocellular carcinoma (HCC) visited his previous hospital due to abdominal pain and was diagnosed with ruptured HCC. Before visiting our hospital, he underwent HCC treatment at his previous hospital, but his tumors did not improve. Although he started treatment with sorafen...

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Detalles Bibliográficos
Autores principales: Yamaoka, Kenji, Kawaoka, Tomokazu, Aikata, Hiroshi, Ando, Yuwa, Kosaka, Yumi, Suehiro, Yosuke, Fujii, Yasutomo, Uchikawa, Shinsuke, Morio, Kei, Fujino, Hatsue, Nakahara, Takashi, Murakami, Eisuke, Yamauchi, Masami, Tsuge, Masataka, Hiramatsu, Akira, Imamura, Michio, Takahashi, Shoichi, Saeki, Yoshihiro, Kuroda, Shintaro, Kobayashi, Tsuyoshi, Ohdan, Hideki, Miyata, Yoshihiro, Okada, Morihito, Chayama, Kazuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313913/
https://www.ncbi.nlm.nih.gov/pubmed/34193774
http://dx.doi.org/10.2169/internalmedicine.5870-20
Descripción
Sumario:A 68-year-old man with hepatocellular carcinoma (HCC) visited his previous hospital due to abdominal pain and was diagnosed with ruptured HCC. Before visiting our hospital, he underwent HCC treatment at his previous hospital, but his tumors did not improve. Although he started treatment with sorafenib, the tumors rapidly grew. Subsequently, regorafenib was given, and the tumors shrank. After 22 months being treated with regorafenib, HCC reoccurred, with a new lung metastasis and a contrast-enhanced nodule on the peritoneal dissemination appearing. He underwent conversion surgery and survived for 4.5 years after his HCC was diagnosed.

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