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AAV Delivery of shRNA Against TRPC6 in Mouse Hippocampus Impairs Cognitive Function
Transient Receptor Potential Canonical 6 (TRPC6) has been suggested to be involved in synapse function and contribute to hippocampal-dependent cognitive processes. Gene silencing of TRPC6 was performed by injecting adeno-associated virus (AAV) expressing TRPC6-specific shRNA (shRNA-TRPC6) into the h...
Autores principales: | Xie, Ruxin, Wang, Zhongke, Liu, Tianyao, Xiao, Rui, Lv, Keyi, Wu, Chuan, Luo, Yi, Cai, Yun, Fan, Xiaotang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313999/ https://www.ncbi.nlm.nih.gov/pubmed/34327201 http://dx.doi.org/10.3389/fcell.2021.688655 |
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