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Acute and 28-days subacute toxicity studies of Gαq-RGS2 signaling inhibitor

BACKGROUND: The aim of study was to evaluate the single oral dose and 28 day repeated oral administration toxicity profile of the synthetic compound Gαq-RGS2 signaling inhibitor, (1-(5-chloro-2-hydroxyphenyl)-3-(4-(trifluoromethyl)phenyl)-1 H-1,2,4-triazol-5(4 H)-one) as per OECD guideline 425 (2008...

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Detalles Bibliográficos
Autores principales: Beladiya, Jayesh V., Mehta, Anita A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8314442/
https://www.ncbi.nlm.nih.gov/pubmed/34311782
http://dx.doi.org/10.1186/s42826-021-00093-1

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