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Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany

We detected delayed and reduced antibody and T-cell responses after BNT162b2 vaccination in 71 elderly persons (median age 81 years) compared with 123 healthcare workers (median age 34 years) in Germany. These data emphasize that nonpharmaceutical interventions for coronavirus disease remain crucial...

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Autores principales: Schwarz, Tatjana, Tober-Lau, Pinkus, Hillus, David, Helbig, Elisa T., Lippert, Lena J., Thibeault, Charlotte, Koch, Willi, Landgraf, Irmgard, Michel, Janine, Bergfeld, Leon, Niemeyer, Daniela, Mühlemann, Barbara, Conrad, Claudia, Dang-Heine, Chantip, Kasper, Stefanie, Münn, Friederike, Kappert, Kai, Nitsche, Andreas, Tauber, Rudolf, Schmidt, Sein, Kopankiewicz, Piotr, Bias, Harald, Seybold, Joachim, von Kalle, Christof, Jones, Terry C., Suttorp, Norbert, Drosten, Christian, Sander, Leif Erik, Corman, Victor M., Kurth, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8314803/
https://www.ncbi.nlm.nih.gov/pubmed/34102097
http://dx.doi.org/10.3201/eid2708.211145
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author Schwarz, Tatjana
Tober-Lau, Pinkus
Hillus, David
Helbig, Elisa T.
Lippert, Lena J.
Thibeault, Charlotte
Koch, Willi
Landgraf, Irmgard
Michel, Janine
Bergfeld, Leon
Niemeyer, Daniela
Mühlemann, Barbara
Conrad, Claudia
Dang-Heine, Chantip
Kasper, Stefanie
Münn, Friederike
Kappert, Kai
Nitsche, Andreas
Tauber, Rudolf
Schmidt, Sein
Kopankiewicz, Piotr
Bias, Harald
Seybold, Joachim
von Kalle, Christof
Jones, Terry C.
Suttorp, Norbert
Drosten, Christian
Sander, Leif Erik
Corman, Victor M.
Kurth, Florian
author_facet Schwarz, Tatjana
Tober-Lau, Pinkus
Hillus, David
Helbig, Elisa T.
Lippert, Lena J.
Thibeault, Charlotte
Koch, Willi
Landgraf, Irmgard
Michel, Janine
Bergfeld, Leon
Niemeyer, Daniela
Mühlemann, Barbara
Conrad, Claudia
Dang-Heine, Chantip
Kasper, Stefanie
Münn, Friederike
Kappert, Kai
Nitsche, Andreas
Tauber, Rudolf
Schmidt, Sein
Kopankiewicz, Piotr
Bias, Harald
Seybold, Joachim
von Kalle, Christof
Jones, Terry C.
Suttorp, Norbert
Drosten, Christian
Sander, Leif Erik
Corman, Victor M.
Kurth, Florian
author_sort Schwarz, Tatjana
collection PubMed
description We detected delayed and reduced antibody and T-cell responses after BNT162b2 vaccination in 71 elderly persons (median age 81 years) compared with 123 healthcare workers (median age 34 years) in Germany. These data emphasize that nonpharmaceutical interventions for coronavirus disease remain crucial and that additional immunizations for the elderly might become necessary.
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spelling pubmed-83148032021-08-07 Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany Schwarz, Tatjana Tober-Lau, Pinkus Hillus, David Helbig, Elisa T. Lippert, Lena J. Thibeault, Charlotte Koch, Willi Landgraf, Irmgard Michel, Janine Bergfeld, Leon Niemeyer, Daniela Mühlemann, Barbara Conrad, Claudia Dang-Heine, Chantip Kasper, Stefanie Münn, Friederike Kappert, Kai Nitsche, Andreas Tauber, Rudolf Schmidt, Sein Kopankiewicz, Piotr Bias, Harald Seybold, Joachim von Kalle, Christof Jones, Terry C. Suttorp, Norbert Drosten, Christian Sander, Leif Erik Corman, Victor M. Kurth, Florian Emerg Infect Dis Dispatch We detected delayed and reduced antibody and T-cell responses after BNT162b2 vaccination in 71 elderly persons (median age 81 years) compared with 123 healthcare workers (median age 34 years) in Germany. These data emphasize that nonpharmaceutical interventions for coronavirus disease remain crucial and that additional immunizations for the elderly might become necessary. Centers for Disease Control and Prevention 2021-08 /pmc/articles/PMC8314803/ /pubmed/34102097 http://dx.doi.org/10.3201/eid2708.211145 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Schwarz, Tatjana
Tober-Lau, Pinkus
Hillus, David
Helbig, Elisa T.
Lippert, Lena J.
Thibeault, Charlotte
Koch, Willi
Landgraf, Irmgard
Michel, Janine
Bergfeld, Leon
Niemeyer, Daniela
Mühlemann, Barbara
Conrad, Claudia
Dang-Heine, Chantip
Kasper, Stefanie
Münn, Friederike
Kappert, Kai
Nitsche, Andreas
Tauber, Rudolf
Schmidt, Sein
Kopankiewicz, Piotr
Bias, Harald
Seybold, Joachim
von Kalle, Christof
Jones, Terry C.
Suttorp, Norbert
Drosten, Christian
Sander, Leif Erik
Corman, Victor M.
Kurth, Florian
Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany
title Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany
title_full Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany
title_fullStr Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany
title_full_unstemmed Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany
title_short Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany
title_sort delayed antibody and t-cell response to bnt162b2 vaccination in the elderly, germany
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8314803/
https://www.ncbi.nlm.nih.gov/pubmed/34102097
http://dx.doi.org/10.3201/eid2708.211145
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