Discovery of Small-Molecule Inhibitors of SARS-CoV-2 Proteins Using a Computational and Experimental Pipeline

A rapid response is necessary to contain emergent biological outbreaks before they can become pandemics. The novel coronavirus (SARS-CoV-2) that causes COVID-19 was first reported in December of 2019 in Wuhan, China and reached most corners of the globe in less than two months. In just over a year s...

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Detalles Bibliográficos
Autores principales: Lau, Edmond Y., Negrete, Oscar A., Bennett, W. F. Drew, Bennion, Brian J., Borucki, Monica, Bourguet, Feliza, Epstein, Aidan, Franco, Magdalena, Harmon, Brooke, He, Stewart, Jones, Derek, Kim, Hyojin, Kirshner, Daniel, Lao, Victoria, Lo, Jacky, McLoughlin, Kevin, Mosesso, Richard, Murugesh, Deepa K., Saada, Edwin A., Segelke, Brent, Stefan, Maxwell A., Stevenson, Garrett A., Torres, Marisa W., Weilhammer, Dina R., Wong, Sergio, Yang, Yue, Zemla, Adam, Zhang, Xiaohua, Zhu, Fangqiang, Allen, Jonathan E., Lightstone, Felice C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315004/
https://www.ncbi.nlm.nih.gov/pubmed/34327214
http://dx.doi.org/10.3389/fmolb.2021.678701

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