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Celastrol ameliorates vascular neointimal hyperplasia through Wnt5a-involved autophagy

Neointimal hyperplasia caused by the excessive proliferation of vascular smooth muscle cells (VSMCs) is the pathological basis of restenosis. However, there are few effective strategies to prevent restenosis. Celastrol, a pentacyclic triterpene, has been recently documented to be beneficial to certa...

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Detalles Bibliográficos
Autores principales: Shi, Ya-Ning, Liu, Le-Ping, Deng, Chang-Feng, Zhao, Tan-Jun, Shi, Zhe, Yan, Jian-Ye, Gong, Yong-Zhen, Liao, Duan-Fang, Qin, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315023/
https://www.ncbi.nlm.nih.gov/pubmed/34326694
http://dx.doi.org/10.7150/ijbs.58715