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Low-dose total body irradiation facilitates antitumoral Th1 immune responses

CD4(+) T helper cells are capable of mediating long-term antitumoral immune responses. We developed a combined immunotherapy (COMBO) using tumor antigen-specific T helper 1 cells (Tag-Th1), dual PD-L1/LAG-3 immune checkpoint blockade, and a low-dose total body irradiation (TBI) of 2 Gy, that was hig...

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Detalles Bibliográficos
Autores principales:	Sonanini, Dominik, Griessinger, Christoph M., Schörg, Barbara F., Knopf, Philipp, Dittmann, Klaus, Röcken, Martin, Pichler, Bernd J., Kneilling, Manfred
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315067/ https://www.ncbi.nlm.nih.gov/pubmed/34335959 http://dx.doi.org/10.7150/thno.61459

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