Thymosin β4 increases cardiac cell proliferation, cell engraftment, and the reparative potency of human induced-pluripotent stem cell-derived cardiomyocytes in a porcine model of acute myocardial infarction

Rationale: Previous studies have shown that human embryonic stem cell-derived cardiomyocytes improved myocardial recovery when administered to infarcted pig and non-human primate hearts. However, the engraftment of intramyocardially delivered cells is poor and the effectiveness of clinically relevan...

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Detalles Bibliográficos
Autores principales: Tan, Shi Hua, Loo, Sze Jie, Gao, Yu, Tao, Zhong Hao, Su, Li Ping, Wang, Chen Xu, Zhang, Sophia L., Mu, Yong Hui, Cui, Ying Hua, Abdurrachim, Desiree, Wang, Wei Hsin, Lalic, Janise, Lim, Kheng Choon, Bu, Jun, Tan, Ru San, Lee, Teck Hock, Zhang, Jianyi, Ye, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315077/
https://www.ncbi.nlm.nih.gov/pubmed/34335970
http://dx.doi.org/10.7150/thno.56757

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