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SpikChIP: a novel computational methodology to compare multiple ChIP-seq using spike-in chromatin
In order to evaluate cell- and disease-specific changes in the interacting strength of chromatin targets, ChIP-seq signal across multiple conditions must undergo robust normalization. However, this is not possible using the standard ChIP-seq scheme, which lacks a reference for the control of biologi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315120/ https://www.ncbi.nlm.nih.gov/pubmed/34327329 http://dx.doi.org/10.1093/nargab/lqab064 |