Structural Deformation of MTX Induced by Nanodrug Conjugation Dictate Intracellular Drug Transport and Drug Efficacy

BACKGROUND: Understanding structural interactions between the active drug and conjugated nanoparticles is critical for optimizing intracellular drug transport and for increasing nano drug efficacy. In this regard, analyzing the conformational deformation of conjugated drugs surrounding nanoparticles...

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Detalles Bibliográficos
Autores principales: Park, Jun-Young, Hyun, Ja-Shil, Jee, Jun-Goo, Park, Sung Jean, Khang, Dongwoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315289/
https://www.ncbi.nlm.nih.gov/pubmed/34326636
http://dx.doi.org/10.2147/IJN.S317231

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