Cargando…

Diagnosis of retinal disorders from Optical Coherence Tomography images using CNN

An efficient automatic decision support system for detection of retinal disorders is important and is the need of the hour. Optical Coherence Tomography (OCT) is the current imaging modality for the early detection of retinal disorders non-invasively. In this work, a Convolution Neural Network (CNN)...

Descripción completa

Detalles Bibliográficos
Autores principales: Rajagopalan, Nithya, N., Venkateswaran, Josephraj, Alex Noel, E., Srithaladevi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315505/
https://www.ncbi.nlm.nih.gov/pubmed/34314421
http://dx.doi.org/10.1371/journal.pone.0254180
_version_ 1783729731894509568
author Rajagopalan, Nithya
N., Venkateswaran
Josephraj, Alex Noel
E., Srithaladevi
author_facet Rajagopalan, Nithya
N., Venkateswaran
Josephraj, Alex Noel
E., Srithaladevi
author_sort Rajagopalan, Nithya
collection PubMed
description An efficient automatic decision support system for detection of retinal disorders is important and is the need of the hour. Optical Coherence Tomography (OCT) is the current imaging modality for the early detection of retinal disorders non-invasively. In this work, a Convolution Neural Network (CNN) model is proposed to classify three types of retinal disorders namely: Choroidal neovascularization (CNV), Drusen macular degeneration (DMD) and Diabetic macular edema (DME). The hyperparameters of the model like batch size, number of epochs, dropout rate, and the type of optimizer are tuned using random search optimization method for better performance to classify different retinal disorders. The proposed architecture provides an accuracy of 97.01%, sensitivity of 93.43%, and 98.07% specificity and it outperformed other existing models, when compared. The proposed model can be used for the large-scale screening of retinal disorders effectively.
format Online
Article
Text
id pubmed-8315505
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-83155052021-07-31 Diagnosis of retinal disorders from Optical Coherence Tomography images using CNN Rajagopalan, Nithya N., Venkateswaran Josephraj, Alex Noel E., Srithaladevi PLoS One Research Article An efficient automatic decision support system for detection of retinal disorders is important and is the need of the hour. Optical Coherence Tomography (OCT) is the current imaging modality for the early detection of retinal disorders non-invasively. In this work, a Convolution Neural Network (CNN) model is proposed to classify three types of retinal disorders namely: Choroidal neovascularization (CNV), Drusen macular degeneration (DMD) and Diabetic macular edema (DME). The hyperparameters of the model like batch size, number of epochs, dropout rate, and the type of optimizer are tuned using random search optimization method for better performance to classify different retinal disorders. The proposed architecture provides an accuracy of 97.01%, sensitivity of 93.43%, and 98.07% specificity and it outperformed other existing models, when compared. The proposed model can be used for the large-scale screening of retinal disorders effectively. Public Library of Science 2021-07-27 /pmc/articles/PMC8315505/ /pubmed/34314421 http://dx.doi.org/10.1371/journal.pone.0254180 Text en © 2021 Rajagopalan et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Rajagopalan, Nithya
N., Venkateswaran
Josephraj, Alex Noel
E., Srithaladevi
Diagnosis of retinal disorders from Optical Coherence Tomography images using CNN
title Diagnosis of retinal disorders from Optical Coherence Tomography images using CNN
title_full Diagnosis of retinal disorders from Optical Coherence Tomography images using CNN
title_fullStr Diagnosis of retinal disorders from Optical Coherence Tomography images using CNN
title_full_unstemmed Diagnosis of retinal disorders from Optical Coherence Tomography images using CNN
title_short Diagnosis of retinal disorders from Optical Coherence Tomography images using CNN
title_sort diagnosis of retinal disorders from optical coherence tomography images using cnn
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315505/
https://www.ncbi.nlm.nih.gov/pubmed/34314421
http://dx.doi.org/10.1371/journal.pone.0254180
work_keys_str_mv AT rajagopalannithya diagnosisofretinaldisordersfromopticalcoherencetomographyimagesusingcnn
AT nvenkateswaran diagnosisofretinaldisordersfromopticalcoherencetomographyimagesusingcnn
AT josephrajalexnoel diagnosisofretinaldisordersfromopticalcoherencetomographyimagesusingcnn
AT esrithaladevi diagnosisofretinaldisordersfromopticalcoherencetomographyimagesusingcnn