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Diagnosis of retinal disorders from Optical Coherence Tomography images using CNN
An efficient automatic decision support system for detection of retinal disorders is important and is the need of the hour. Optical Coherence Tomography (OCT) is the current imaging modality for the early detection of retinal disorders non-invasively. In this work, a Convolution Neural Network (CNN)...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315505/ https://www.ncbi.nlm.nih.gov/pubmed/34314421 http://dx.doi.org/10.1371/journal.pone.0254180 |
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author | Rajagopalan, Nithya N., Venkateswaran Josephraj, Alex Noel E., Srithaladevi |
author_facet | Rajagopalan, Nithya N., Venkateswaran Josephraj, Alex Noel E., Srithaladevi |
author_sort | Rajagopalan, Nithya |
collection | PubMed |
description | An efficient automatic decision support system for detection of retinal disorders is important and is the need of the hour. Optical Coherence Tomography (OCT) is the current imaging modality for the early detection of retinal disorders non-invasively. In this work, a Convolution Neural Network (CNN) model is proposed to classify three types of retinal disorders namely: Choroidal neovascularization (CNV), Drusen macular degeneration (DMD) and Diabetic macular edema (DME). The hyperparameters of the model like batch size, number of epochs, dropout rate, and the type of optimizer are tuned using random search optimization method for better performance to classify different retinal disorders. The proposed architecture provides an accuracy of 97.01%, sensitivity of 93.43%, and 98.07% specificity and it outperformed other existing models, when compared. The proposed model can be used for the large-scale screening of retinal disorders effectively. |
format | Online Article Text |
id | pubmed-8315505 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-83155052021-07-31 Diagnosis of retinal disorders from Optical Coherence Tomography images using CNN Rajagopalan, Nithya N., Venkateswaran Josephraj, Alex Noel E., Srithaladevi PLoS One Research Article An efficient automatic decision support system for detection of retinal disorders is important and is the need of the hour. Optical Coherence Tomography (OCT) is the current imaging modality for the early detection of retinal disorders non-invasively. In this work, a Convolution Neural Network (CNN) model is proposed to classify three types of retinal disorders namely: Choroidal neovascularization (CNV), Drusen macular degeneration (DMD) and Diabetic macular edema (DME). The hyperparameters of the model like batch size, number of epochs, dropout rate, and the type of optimizer are tuned using random search optimization method for better performance to classify different retinal disorders. The proposed architecture provides an accuracy of 97.01%, sensitivity of 93.43%, and 98.07% specificity and it outperformed other existing models, when compared. The proposed model can be used for the large-scale screening of retinal disorders effectively. Public Library of Science 2021-07-27 /pmc/articles/PMC8315505/ /pubmed/34314421 http://dx.doi.org/10.1371/journal.pone.0254180 Text en © 2021 Rajagopalan et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Rajagopalan, Nithya N., Venkateswaran Josephraj, Alex Noel E., Srithaladevi Diagnosis of retinal disorders from Optical Coherence Tomography images using CNN |
title | Diagnosis of retinal disorders from Optical Coherence Tomography images using CNN |
title_full | Diagnosis of retinal disorders from Optical Coherence Tomography images using CNN |
title_fullStr | Diagnosis of retinal disorders from Optical Coherence Tomography images using CNN |
title_full_unstemmed | Diagnosis of retinal disorders from Optical Coherence Tomography images using CNN |
title_short | Diagnosis of retinal disorders from Optical Coherence Tomography images using CNN |
title_sort | diagnosis of retinal disorders from optical coherence tomography images using cnn |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315505/ https://www.ncbi.nlm.nih.gov/pubmed/34314421 http://dx.doi.org/10.1371/journal.pone.0254180 |
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