Cargando…
Cancer stem cells, epithelial-mesenchymal transition, ATP and their roles in drug resistance in cancer
The cancer stem cell (CSC) state and epithelial-mesenchymal transition (EMT) activation are tightly interconnected. Cancer cells that acquire the EMT/CSC phenotype are equipped with adaptive metabolic changes to maintain low reactive oxygen species levels and stemness, enhanced drug transporters, an...
Autores principales: | Zhang, Haiyun, Steed, Alexander, Co, Milo, Chen, Xiaozhuo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
OAE Publishing Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315560/ https://www.ncbi.nlm.nih.gov/pubmed/34322664 http://dx.doi.org/10.20517/cdr.2021.32 |
Ejemplares similares
-
Extracellular and macropinocytosis internalized ATP work together to induce epithelial–mesenchymal transition and other early metastatic activities in lung cancer
por: Cao, Yanyang, et al.
Publicado: (2019) -
An emerging master inducer and regulator for epithelial-mesenchymal transition and tumor metastasis: extracellular and intracellular ATP and its molecular functions and therapeutic potential
por: Cao, Yanyang, et al.
Publicado: (2023) -
Extracellular ATP, as an energy and phosphorylating molecule, induces different types of drug resistances in cancer cells through ATP internalization and intracellular ATP level increase
por: Wang, Xuan, et al.
Publicado: (2017) -
Drug resistance and combating drug resistance in cancer
por: Wang, Xuan, et al.
Publicado: (2019) -
From Transcriptomics, Metabolomics to Functional Studies: Extracellular ATP Induces TGF-β-Like Epithelial Mesenchymal Transition in Lung Cancer Cells
por: Evers, Maria, et al.
Publicado: (2022)