The Role of lncRNA PCAT6 in Cancers
Long non-coding RNA (lncRNA) PCAT6 is a member of the Prostate Cancer Associated Transcripts family of molecules. In this review, we focus on the latest studies involving PCAT6 in the diagnosis, treatment, and prognosis of malignant tumors of the digestive, respiratory, urinary, reproductive, motion...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315724/ https://www.ncbi.nlm.nih.gov/pubmed/34327141 http://dx.doi.org/10.3389/fonc.2021.701495 |
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author | Wang, Siying Chen, Zhenyao Gu, Jingyao Chen, Xin Wang, Zhaoxia |
author_facet | Wang, Siying Chen, Zhenyao Gu, Jingyao Chen, Xin Wang, Zhaoxia |
author_sort | Wang, Siying |
collection | PubMed |
description | Long non-coding RNA (lncRNA) PCAT6 is a member of the Prostate Cancer Associated Transcripts family of molecules. In this review, we focus on the latest studies involving PCAT6 in the diagnosis, treatment, and prognosis of malignant tumors of the digestive, respiratory, urinary, reproductive, motion, and nervous systems. PCAT6 was found to be highly expressed in gastric cancer, colon cancer, hepatocellular carcinoma, lung cancer, bladder cancer, ovarian cancer, breast cancer, cervical cancer, osteosarcoma, glioblastoma, and other tumors. PCAT6 can promote the development and progression of different types of malignant tumors through various mechanisms. Overall, these findings suggest that PCAT6 may play an increasingly vital role in the clinical assessment of these malignant tumors. It can function as an oncogene and may be used as a potential new prognostic biomarker of these tumors. |
format | Online Article Text |
id | pubmed-8315724 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-83157242021-07-28 The Role of lncRNA PCAT6 in Cancers Wang, Siying Chen, Zhenyao Gu, Jingyao Chen, Xin Wang, Zhaoxia Front Oncol Oncology Long non-coding RNA (lncRNA) PCAT6 is a member of the Prostate Cancer Associated Transcripts family of molecules. In this review, we focus on the latest studies involving PCAT6 in the diagnosis, treatment, and prognosis of malignant tumors of the digestive, respiratory, urinary, reproductive, motion, and nervous systems. PCAT6 was found to be highly expressed in gastric cancer, colon cancer, hepatocellular carcinoma, lung cancer, bladder cancer, ovarian cancer, breast cancer, cervical cancer, osteosarcoma, glioblastoma, and other tumors. PCAT6 can promote the development and progression of different types of malignant tumors through various mechanisms. Overall, these findings suggest that PCAT6 may play an increasingly vital role in the clinical assessment of these malignant tumors. It can function as an oncogene and may be used as a potential new prognostic biomarker of these tumors. Frontiers Media S.A. 2021-07-13 /pmc/articles/PMC8315724/ /pubmed/34327141 http://dx.doi.org/10.3389/fonc.2021.701495 Text en Copyright © 2021 Wang, Chen, Gu, Chen and Wang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology Wang, Siying Chen, Zhenyao Gu, Jingyao Chen, Xin Wang, Zhaoxia The Role of lncRNA PCAT6 in Cancers |
title | The Role of lncRNA PCAT6 in Cancers |
title_full | The Role of lncRNA PCAT6 in Cancers |
title_fullStr | The Role of lncRNA PCAT6 in Cancers |
title_full_unstemmed | The Role of lncRNA PCAT6 in Cancers |
title_short | The Role of lncRNA PCAT6 in Cancers |
title_sort | role of lncrna pcat6 in cancers |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315724/ https://www.ncbi.nlm.nih.gov/pubmed/34327141 http://dx.doi.org/10.3389/fonc.2021.701495 |
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