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Improving statistical power in severe malaria genetic association studies by augmenting phenotypic precision
Severe falciparum malaria has substantially affected human evolution. Genetic association studies of patients with clinically defined severe malaria and matched population controls have helped characterise human genetic susceptibility to severe malaria, but phenotypic imprecision compromises discove...
Autores principales: | Watson, James A, Ndila, Carolyne M, Uyoga, Sophie, Macharia, Alexander, Nyutu, Gideon, Mohammed, Shebe, Ngetsa, Caroline, Mturi, Neema, Peshu, Norbert, Tsofa, Benjamin, Rockett, Kirk, Leopold, Stije, Kingston, Hugh, George, Elizabeth C, Maitland, Kathryn, Day, Nicholas PJ, Dondorp, Arjen M, Bejon, Philip, Williams, Thomas N, Holmes, Chris C, White, Nicholas J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315799/ https://www.ncbi.nlm.nih.gov/pubmed/34225842 http://dx.doi.org/10.7554/eLife.69698 |
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