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Improving statistical power in severe malaria genetic association studies by augmenting phenotypic precision

Severe falciparum malaria has substantially affected human evolution. Genetic association studies of patients with clinically defined severe malaria and matched population controls have helped characterise human genetic susceptibility to severe malaria, but phenotypic imprecision compromises discove...

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Detalles Bibliográficos
Autores principales: Watson, James A, Ndila, Carolyne M, Uyoga, Sophie, Macharia, Alexander, Nyutu, Gideon, Mohammed, Shebe, Ngetsa, Caroline, Mturi, Neema, Peshu, Norbert, Tsofa, Benjamin, Rockett, Kirk, Leopold, Stije, Kingston, Hugh, George, Elizabeth C, Maitland, Kathryn, Day, Nicholas PJ, Dondorp, Arjen M, Bejon, Philip, Williams, Thomas N, Holmes, Chris C, White, Nicholas J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315799/
https://www.ncbi.nlm.nih.gov/pubmed/34225842
http://dx.doi.org/10.7554/eLife.69698

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