miR-1 coordinately regulates lysosomal v-ATPase and biogenesis to impact proteotoxicity and muscle function during aging

Muscle function relies on the precise architecture of dynamic contractile elements, which must be fine-tuned to maintain motility throughout life. Muscle is also plastic, and remodeled in response to stress, growth, neural and metabolic inputs. The conserved muscle-enriched microRNA, miR-1, regulate...

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Detalles Bibliográficos
Autores principales: Schiffer, Isabelle, Gerisch, Birgit, Kawamura, Kazuto, Laboy, Raymond, Hewitt, Jennifer, Denzel, Martin Sebastian, Mori, Marcelo A, Vanapalli, Siva, Shen, Yidong, Symmons, Orsolya, Antebi, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315803/
https://www.ncbi.nlm.nih.gov/pubmed/34311841
http://dx.doi.org/10.7554/eLife.66768

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