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Analysis of Blood Biochemistry of Free Ranging and Human-Managed Southern White Rhinoceros (Ceratotherium simum simum) Using the i-STAT Alinity v®

Handheld point-of-care blood analyzers deliver rapid results for biochemical and hematologic parameters, making them very useful in veterinary clinics and in fieldwork applications. This study compared the biochemical and hematologic parameters generated by the novel point-of-care analyzer i-STAT® A...

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Autores principales: Trivedi, Shweta, Burnham, Christina M., Capobianco, Christian M., Boshoff, Christiaan, Zheng, Yaxin, Pettiglio, Jordan Wood, Ange-van Heugten, Kimberly, Bissell, Heidi D., Minter, Larry J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315869/
https://www.ncbi.nlm.nih.gov/pubmed/34336179
http://dx.doi.org/10.1155/2021/2665956
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author Trivedi, Shweta
Burnham, Christina M.
Capobianco, Christian M.
Boshoff, Christiaan
Zheng, Yaxin
Pettiglio, Jordan Wood
Ange-van Heugten, Kimberly
Bissell, Heidi D.
Minter, Larry J.
author_facet Trivedi, Shweta
Burnham, Christina M.
Capobianco, Christian M.
Boshoff, Christiaan
Zheng, Yaxin
Pettiglio, Jordan Wood
Ange-van Heugten, Kimberly
Bissell, Heidi D.
Minter, Larry J.
author_sort Trivedi, Shweta
collection PubMed
description Handheld point-of-care blood analyzers deliver rapid results for biochemical and hematologic parameters, making them very useful in veterinary clinics and in fieldwork applications. This study compared the biochemical and hematologic parameters generated by the novel point-of-care analyzer i-STAT® Alinity V CHEM8+ cartridge between human-managed and free ranging populations of southern white rhinoceros (Ceratotherium simum simum). In addition, a novel reference interval for ionized calcium (iCa), a parameter of diagnostic and prognostic importance, was established for southern white rhinoceros. Blood samples were obtained from 10 managed (6 at NC Zoo and 4 at Busch Gardens Tampa Bay in 2019) and 30 free ranging white rhinoceros (collected in South Africa between 2018 and 2019) and analyzed using the i-STAT. Multiple parameters were higher (P < 0.05) in free ranging versus managed animals including potassium, blood urea nitrogen, creatinine, glucose, hematocrit, and hemoglobin. Conversely, iCa concentrations were higher (P < 0.05) in the managed populations of white rhinoceros. The RI determined for iCa was 1.36–1.56 mmol/L, with a mean of 1.46 mmol/L, and was determined using the guidelines from the American Society for Veterinary Clinical Pathology. There was no difference in anion gap, chlorine, total carbon dioxide, or sodium between the populations. Seasonality and locality of sampling as well as diet may be contributing factors to the higher iCa concentrations in managed rhinoceros. The six elevated parameters in free ranging rhinoceros are likely attributable to dehydration compounded by capture stress. This data provides insight into the state of several biochemical and hematologic parameters in southern white rhinoceros and will allow veterinarians to better assess the health of both managed and free ranging populations.
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spelling pubmed-83158692021-07-31 Analysis of Blood Biochemistry of Free Ranging and Human-Managed Southern White Rhinoceros (Ceratotherium simum simum) Using the i-STAT Alinity v® Trivedi, Shweta Burnham, Christina M. Capobianco, Christian M. Boshoff, Christiaan Zheng, Yaxin Pettiglio, Jordan Wood Ange-van Heugten, Kimberly Bissell, Heidi D. Minter, Larry J. Vet Med Int Research Article Handheld point-of-care blood analyzers deliver rapid results for biochemical and hematologic parameters, making them very useful in veterinary clinics and in fieldwork applications. This study compared the biochemical and hematologic parameters generated by the novel point-of-care analyzer i-STAT® Alinity V CHEM8+ cartridge between human-managed and free ranging populations of southern white rhinoceros (Ceratotherium simum simum). In addition, a novel reference interval for ionized calcium (iCa), a parameter of diagnostic and prognostic importance, was established for southern white rhinoceros. Blood samples were obtained from 10 managed (6 at NC Zoo and 4 at Busch Gardens Tampa Bay in 2019) and 30 free ranging white rhinoceros (collected in South Africa between 2018 and 2019) and analyzed using the i-STAT. Multiple parameters were higher (P < 0.05) in free ranging versus managed animals including potassium, blood urea nitrogen, creatinine, glucose, hematocrit, and hemoglobin. Conversely, iCa concentrations were higher (P < 0.05) in the managed populations of white rhinoceros. The RI determined for iCa was 1.36–1.56 mmol/L, with a mean of 1.46 mmol/L, and was determined using the guidelines from the American Society for Veterinary Clinical Pathology. There was no difference in anion gap, chlorine, total carbon dioxide, or sodium between the populations. Seasonality and locality of sampling as well as diet may be contributing factors to the higher iCa concentrations in managed rhinoceros. The six elevated parameters in free ranging rhinoceros are likely attributable to dehydration compounded by capture stress. This data provides insight into the state of several biochemical and hematologic parameters in southern white rhinoceros and will allow veterinarians to better assess the health of both managed and free ranging populations. Hindawi 2021-07-19 /pmc/articles/PMC8315869/ /pubmed/34336179 http://dx.doi.org/10.1155/2021/2665956 Text en Copyright © 2021 Shweta Trivedi et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Trivedi, Shweta
Burnham, Christina M.
Capobianco, Christian M.
Boshoff, Christiaan
Zheng, Yaxin
Pettiglio, Jordan Wood
Ange-van Heugten, Kimberly
Bissell, Heidi D.
Minter, Larry J.
Analysis of Blood Biochemistry of Free Ranging and Human-Managed Southern White Rhinoceros (Ceratotherium simum simum) Using the i-STAT Alinity v®
title Analysis of Blood Biochemistry of Free Ranging and Human-Managed Southern White Rhinoceros (Ceratotherium simum simum) Using the i-STAT Alinity v®
title_full Analysis of Blood Biochemistry of Free Ranging and Human-Managed Southern White Rhinoceros (Ceratotherium simum simum) Using the i-STAT Alinity v®
title_fullStr Analysis of Blood Biochemistry of Free Ranging and Human-Managed Southern White Rhinoceros (Ceratotherium simum simum) Using the i-STAT Alinity v®
title_full_unstemmed Analysis of Blood Biochemistry of Free Ranging and Human-Managed Southern White Rhinoceros (Ceratotherium simum simum) Using the i-STAT Alinity v®
title_short Analysis of Blood Biochemistry of Free Ranging and Human-Managed Southern White Rhinoceros (Ceratotherium simum simum) Using the i-STAT Alinity v®
title_sort analysis of blood biochemistry of free ranging and human-managed southern white rhinoceros (ceratotherium simum simum) using the i-stat alinity v®
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315869/
https://www.ncbi.nlm.nih.gov/pubmed/34336179
http://dx.doi.org/10.1155/2021/2665956
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