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The Auxiliary Diagnosis and Imaging Characteristics of MRI Combined with CT in Patients with Cholangiocarcinoma

BACKGROUND: Patients with cholangiocarcinoma (CCA) have poor prognosis and high mortality. Therefore, early detection and early diagnosis are extremely important to control the development of CCA. This study aims to explore the diagnostic effect in patients with CCA and imaging characteristics of MR...

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Autores principales: Li, Jing, Yu, Yuanlin, He, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315873/
https://www.ncbi.nlm.nih.gov/pubmed/34335752
http://dx.doi.org/10.1155/2021/2790958
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author Li, Jing
Yu, Yuanlin
He, Qing
author_facet Li, Jing
Yu, Yuanlin
He, Qing
author_sort Li, Jing
collection PubMed
description BACKGROUND: Patients with cholangiocarcinoma (CCA) have poor prognosis and high mortality. Therefore, early detection and early diagnosis are extremely important to control the development of CCA. This study aims to explore the diagnostic effect in patients with CCA and imaging characteristics of MRI combined with CT. METHODS: 109 patients with suspected CCA underwent CT and MRI before diagnosis. The examination results were compared with the “gold standard.” ROC curve was drawn to analyze the diagnostic efficacy of MRI combined with CT for CCA patients. RESULTS: The diagnosis rate of suspected CCA patients was 95.41%. The diagnostic coincidence rate of CT and MRI examination was 89.42% and 92.31%, respectively. The diagnostic coincidence rate of MRI combined with CT examination was 100.00%. The number of CT delayed enhancement, peripheral bile duct dilatation, and hepatic capsular depression were more than those of MRI. The number of circular enhancement cases in the CT group was less than that in the MRI group. ROC curve results showed that the sensitivity and specificity of MRI combined with CT for the diagnosis of CCA patients were higher than those of MRI or CT alone. CONCLUSION: MRI combined with CT has high diagnostic sensitivity and specificity and can provide imaging evidence for the clinical diagnosis and treatment of CCA.
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spelling pubmed-83158732021-07-31 The Auxiliary Diagnosis and Imaging Characteristics of MRI Combined with CT in Patients with Cholangiocarcinoma Li, Jing Yu, Yuanlin He, Qing J Oncol Research Article BACKGROUND: Patients with cholangiocarcinoma (CCA) have poor prognosis and high mortality. Therefore, early detection and early diagnosis are extremely important to control the development of CCA. This study aims to explore the diagnostic effect in patients with CCA and imaging characteristics of MRI combined with CT. METHODS: 109 patients with suspected CCA underwent CT and MRI before diagnosis. The examination results were compared with the “gold standard.” ROC curve was drawn to analyze the diagnostic efficacy of MRI combined with CT for CCA patients. RESULTS: The diagnosis rate of suspected CCA patients was 95.41%. The diagnostic coincidence rate of CT and MRI examination was 89.42% and 92.31%, respectively. The diagnostic coincidence rate of MRI combined with CT examination was 100.00%. The number of CT delayed enhancement, peripheral bile duct dilatation, and hepatic capsular depression were more than those of MRI. The number of circular enhancement cases in the CT group was less than that in the MRI group. ROC curve results showed that the sensitivity and specificity of MRI combined with CT for the diagnosis of CCA patients were higher than those of MRI or CT alone. CONCLUSION: MRI combined with CT has high diagnostic sensitivity and specificity and can provide imaging evidence for the clinical diagnosis and treatment of CCA. Hindawi 2021-07-16 /pmc/articles/PMC8315873/ /pubmed/34335752 http://dx.doi.org/10.1155/2021/2790958 Text en Copyright © 2021 Jing Li et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Li, Jing
Yu, Yuanlin
He, Qing
The Auxiliary Diagnosis and Imaging Characteristics of MRI Combined with CT in Patients with Cholangiocarcinoma
title The Auxiliary Diagnosis and Imaging Characteristics of MRI Combined with CT in Patients with Cholangiocarcinoma
title_full The Auxiliary Diagnosis and Imaging Characteristics of MRI Combined with CT in Patients with Cholangiocarcinoma
title_fullStr The Auxiliary Diagnosis and Imaging Characteristics of MRI Combined with CT in Patients with Cholangiocarcinoma
title_full_unstemmed The Auxiliary Diagnosis and Imaging Characteristics of MRI Combined with CT in Patients with Cholangiocarcinoma
title_short The Auxiliary Diagnosis and Imaging Characteristics of MRI Combined with CT in Patients with Cholangiocarcinoma
title_sort auxiliary diagnosis and imaging characteristics of mri combined with ct in patients with cholangiocarcinoma
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315873/
https://www.ncbi.nlm.nih.gov/pubmed/34335752
http://dx.doi.org/10.1155/2021/2790958
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