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J Point and ST Elevation Resembling Brugada: A Marker of Mortality in Methanol Toxicity
OBJECTIVE: J point and coved ST elevation in right precordial leads (not produced by coronary artery disease) are still a matter of challenge, especially when resembling Brugada patients. This clinical entity, among asymptomatic individuals with no family history of sudden cardiac death, would be re...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315878/ https://www.ncbi.nlm.nih.gov/pubmed/34336271 http://dx.doi.org/10.1155/2021/5541385 |
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author | Nikoo, Mohammad Hossein Estedal, Alireza Khatami, Kiana Pakfetrat, Maryam Arjangzadeh, Alireza Boogar, Shahrokh Sadeghi Danesh, Sina Heydari, Seyed Taghi |
author_facet | Nikoo, Mohammad Hossein Estedal, Alireza Khatami, Kiana Pakfetrat, Maryam Arjangzadeh, Alireza Boogar, Shahrokh Sadeghi Danesh, Sina Heydari, Seyed Taghi |
author_sort | Nikoo, Mohammad Hossein |
collection | PubMed |
description | OBJECTIVE: J point and coved ST elevation in right precordial leads (not produced by coronary artery disease) are still a matter of challenge, especially when resembling Brugada patients. This clinical entity, among asymptomatic individuals with no family history of sudden cardiac death, would be reported in some severely ill patients before ventricular fibrillation. This study investigated the relationship between the electrocardiograms with demographic and laboratory data and also analyzed their association with mortality rate among patients with methanol poisoning. METHODS: The sample consisted of 356 patients who were hospitalized with a diagnosis of methanol poisoning in Faghihi and Namazi Hospitals in Shiraz, Southern Iran, in March and April 2020. In this period, a major outbreak of methanol poisoning had occurred in this area. Furthermore, the study used the data on any recorded complications or mortality during hospital course. RESULTS: The ECG (BrP) was observed in a total of 20 (5.6%) patients. Its presence was associated with increased mortality, Glasgow coma scale score <3, and blood sugar levels and was inversely associated with PH, O(2) saturation, and calcium levels (P < 0.05). CONCLUSIONS: This study found that certain ECG patterns and laboratory data can be used as prognostic factors of morbidity and mortality in patients with methanol intoxication. Electrocardiography machines are widely available tools, which can be easily used for risk stratification based on the presence of Brugada approximating electrocardiograms among patients with methanol intoxication. |
format | Online Article Text |
id | pubmed-8315878 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-83158782021-07-31 J Point and ST Elevation Resembling Brugada: A Marker of Mortality in Methanol Toxicity Nikoo, Mohammad Hossein Estedal, Alireza Khatami, Kiana Pakfetrat, Maryam Arjangzadeh, Alireza Boogar, Shahrokh Sadeghi Danesh, Sina Heydari, Seyed Taghi Cardiol Res Pract Research Article OBJECTIVE: J point and coved ST elevation in right precordial leads (not produced by coronary artery disease) are still a matter of challenge, especially when resembling Brugada patients. This clinical entity, among asymptomatic individuals with no family history of sudden cardiac death, would be reported in some severely ill patients before ventricular fibrillation. This study investigated the relationship between the electrocardiograms with demographic and laboratory data and also analyzed their association with mortality rate among patients with methanol poisoning. METHODS: The sample consisted of 356 patients who were hospitalized with a diagnosis of methanol poisoning in Faghihi and Namazi Hospitals in Shiraz, Southern Iran, in March and April 2020. In this period, a major outbreak of methanol poisoning had occurred in this area. Furthermore, the study used the data on any recorded complications or mortality during hospital course. RESULTS: The ECG (BrP) was observed in a total of 20 (5.6%) patients. Its presence was associated with increased mortality, Glasgow coma scale score <3, and blood sugar levels and was inversely associated with PH, O(2) saturation, and calcium levels (P < 0.05). CONCLUSIONS: This study found that certain ECG patterns and laboratory data can be used as prognostic factors of morbidity and mortality in patients with methanol intoxication. Electrocardiography machines are widely available tools, which can be easily used for risk stratification based on the presence of Brugada approximating electrocardiograms among patients with methanol intoxication. Hindawi 2021-07-19 /pmc/articles/PMC8315878/ /pubmed/34336271 http://dx.doi.org/10.1155/2021/5541385 Text en Copyright © 2021 Mohammad Hossein Nikoo et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Nikoo, Mohammad Hossein Estedal, Alireza Khatami, Kiana Pakfetrat, Maryam Arjangzadeh, Alireza Boogar, Shahrokh Sadeghi Danesh, Sina Heydari, Seyed Taghi J Point and ST Elevation Resembling Brugada: A Marker of Mortality in Methanol Toxicity |
title | J Point and ST Elevation Resembling Brugada: A Marker of Mortality in Methanol Toxicity |
title_full | J Point and ST Elevation Resembling Brugada: A Marker of Mortality in Methanol Toxicity |
title_fullStr | J Point and ST Elevation Resembling Brugada: A Marker of Mortality in Methanol Toxicity |
title_full_unstemmed | J Point and ST Elevation Resembling Brugada: A Marker of Mortality in Methanol Toxicity |
title_short | J Point and ST Elevation Resembling Brugada: A Marker of Mortality in Methanol Toxicity |
title_sort | j point and st elevation resembling brugada: a marker of mortality in methanol toxicity |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315878/ https://www.ncbi.nlm.nih.gov/pubmed/34336271 http://dx.doi.org/10.1155/2021/5541385 |
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