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J Point and ST Elevation Resembling Brugada: A Marker of Mortality in Methanol Toxicity

OBJECTIVE: J point and coved ST elevation in right precordial leads (not produced by coronary artery disease) are still a matter of challenge, especially when resembling Brugada patients. This clinical entity, among asymptomatic individuals with no family history of sudden cardiac death, would be re...

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Autores principales: Nikoo, Mohammad Hossein, Estedal, Alireza, Khatami, Kiana, Pakfetrat, Maryam, Arjangzadeh, Alireza, Boogar, Shahrokh Sadeghi, Danesh, Sina, Heydari, Seyed Taghi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315878/
https://www.ncbi.nlm.nih.gov/pubmed/34336271
http://dx.doi.org/10.1155/2021/5541385
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author Nikoo, Mohammad Hossein
Estedal, Alireza
Khatami, Kiana
Pakfetrat, Maryam
Arjangzadeh, Alireza
Boogar, Shahrokh Sadeghi
Danesh, Sina
Heydari, Seyed Taghi
author_facet Nikoo, Mohammad Hossein
Estedal, Alireza
Khatami, Kiana
Pakfetrat, Maryam
Arjangzadeh, Alireza
Boogar, Shahrokh Sadeghi
Danesh, Sina
Heydari, Seyed Taghi
author_sort Nikoo, Mohammad Hossein
collection PubMed
description OBJECTIVE: J point and coved ST elevation in right precordial leads (not produced by coronary artery disease) are still a matter of challenge, especially when resembling Brugada patients. This clinical entity, among asymptomatic individuals with no family history of sudden cardiac death, would be reported in some severely ill patients before ventricular fibrillation. This study investigated the relationship between the electrocardiograms with demographic and laboratory data and also analyzed their association with mortality rate among patients with methanol poisoning. METHODS: The sample consisted of 356 patients who were hospitalized with a diagnosis of methanol poisoning in Faghihi and Namazi Hospitals in Shiraz, Southern Iran, in March and April 2020. In this period, a major outbreak of methanol poisoning had occurred in this area. Furthermore, the study used the data on any recorded complications or mortality during hospital course. RESULTS: The ECG (BrP) was observed in a total of 20 (5.6%) patients. Its presence was associated with increased mortality, Glasgow coma scale score <3, and blood sugar levels and was inversely associated with PH, O(2) saturation, and calcium levels (P < 0.05). CONCLUSIONS: This study found that certain ECG patterns and laboratory data can be used as prognostic factors of morbidity and mortality in patients with methanol intoxication. Electrocardiography machines are widely available tools, which can be easily used for risk stratification based on the presence of Brugada approximating electrocardiograms among patients with methanol intoxication.
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spelling pubmed-83158782021-07-31 J Point and ST Elevation Resembling Brugada: A Marker of Mortality in Methanol Toxicity Nikoo, Mohammad Hossein Estedal, Alireza Khatami, Kiana Pakfetrat, Maryam Arjangzadeh, Alireza Boogar, Shahrokh Sadeghi Danesh, Sina Heydari, Seyed Taghi Cardiol Res Pract Research Article OBJECTIVE: J point and coved ST elevation in right precordial leads (not produced by coronary artery disease) are still a matter of challenge, especially when resembling Brugada patients. This clinical entity, among asymptomatic individuals with no family history of sudden cardiac death, would be reported in some severely ill patients before ventricular fibrillation. This study investigated the relationship between the electrocardiograms with demographic and laboratory data and also analyzed their association with mortality rate among patients with methanol poisoning. METHODS: The sample consisted of 356 patients who were hospitalized with a diagnosis of methanol poisoning in Faghihi and Namazi Hospitals in Shiraz, Southern Iran, in March and April 2020. In this period, a major outbreak of methanol poisoning had occurred in this area. Furthermore, the study used the data on any recorded complications or mortality during hospital course. RESULTS: The ECG (BrP) was observed in a total of 20 (5.6%) patients. Its presence was associated with increased mortality, Glasgow coma scale score <3, and blood sugar levels and was inversely associated with PH, O(2) saturation, and calcium levels (P < 0.05). CONCLUSIONS: This study found that certain ECG patterns and laboratory data can be used as prognostic factors of morbidity and mortality in patients with methanol intoxication. Electrocardiography machines are widely available tools, which can be easily used for risk stratification based on the presence of Brugada approximating electrocardiograms among patients with methanol intoxication. Hindawi 2021-07-19 /pmc/articles/PMC8315878/ /pubmed/34336271 http://dx.doi.org/10.1155/2021/5541385 Text en Copyright © 2021 Mohammad Hossein Nikoo et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Nikoo, Mohammad Hossein
Estedal, Alireza
Khatami, Kiana
Pakfetrat, Maryam
Arjangzadeh, Alireza
Boogar, Shahrokh Sadeghi
Danesh, Sina
Heydari, Seyed Taghi
J Point and ST Elevation Resembling Brugada: A Marker of Mortality in Methanol Toxicity
title J Point and ST Elevation Resembling Brugada: A Marker of Mortality in Methanol Toxicity
title_full J Point and ST Elevation Resembling Brugada: A Marker of Mortality in Methanol Toxicity
title_fullStr J Point and ST Elevation Resembling Brugada: A Marker of Mortality in Methanol Toxicity
title_full_unstemmed J Point and ST Elevation Resembling Brugada: A Marker of Mortality in Methanol Toxicity
title_short J Point and ST Elevation Resembling Brugada: A Marker of Mortality in Methanol Toxicity
title_sort j point and st elevation resembling brugada: a marker of mortality in methanol toxicity
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315878/
https://www.ncbi.nlm.nih.gov/pubmed/34336271
http://dx.doi.org/10.1155/2021/5541385
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