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Neuronal activity-induced BRG1 phosphorylation regulates enhancer activation

Neuronal activity-induced enhancers drive gene activation. We demonstrate that BRG1, the core subunit of SWI/SNF-like BAF ATP-dependent chromatin remodeling complexes, regulates neuronal activity-induced enhancers. Upon stimulation, BRG1 is recruited to enhancers in an H3K27Ac-dependent manner. BRG1...

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Detalles Bibliográficos
Autores principales: Kim, BongWoo, Luo, Yi, Zhan, Xiaoming, Zhang, Zilai, Shi, Xuanming, Yi, Jiaqing, Xuan, Zhenyu, Wu, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315893/
https://www.ncbi.nlm.nih.gov/pubmed/34260936
http://dx.doi.org/10.1016/j.celrep.2021.109357

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