Inhibition of Escherichia coli Lipoprotein Diacylglyceryl Transferase Is Insensitive to Resistance Caused by Deletion of Braun’s Lipoprotein

Lipoprotein diacylglyceryl transferase (Lgt) catalyzes the first step in the biogenesis of Gram-negative bacterial lipoproteins which play crucial roles in bacterial growth and pathogenesis. We demonstrate that Lgt depletion in a clinical uropathogenic Escherichia coli strain leads to permeabilizati...

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Detalles Bibliográficos
Autores principales: Diao, Jingyu, Komura, Rie, Sano, Tatsuya, Pantua, Homer, Storek, Kelly M., Inaba, Hiroko, Ogawa, Haruhiko, Noland, Cameron L., Peng, Yutian, Gloor, Susan L., Yan, Donghong, Kang, Jing, Katakam, Anand Kumar, Volny, Michael, Liu, Peter, Nickerson, Nicholas N., Sandoval, Wendy, Austin, Cary D., Murray, Jeremy, Rutherford, Steven T., Reichelt, Mike, Xu, Yiming, Xu, Min, Yanagida, Hayato, Nishikawa, Junichi, Reid, Patrick C., Cunningham, Christian N., Kapadia, Sharookh B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316002/
https://www.ncbi.nlm.nih.gov/pubmed/33875545
http://dx.doi.org/10.1128/JB.00149-21

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