Cargando…
No evidence of human genome integration of SARS-CoV-2 found by long-read DNA sequencing
A recent study proposed that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) hijacks the LINE-1 (L1) retrotransposition machinery to integrate into the DNA of infected cells. If confirmed, this finding could have significant clinical implications. Here, we apply deep (>50×) long-read...
Autores principales: | Smits, Nathan, Rasmussen, Jay, Bodea, Gabriela O., Amarilla, Alberto A., Gerdes, Patricia, Sanchez-Luque, Francisco J., Ajjikuttira, Prabha, Modhiran, Naphak, Liang, Benjamin, Faivre, Jamila, Deveson, Ira W., Khromykh, Alexander A., Watterson, Daniel, Ewing, Adam D., Faulkner, Geoffrey J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s).
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316065/ https://www.ncbi.nlm.nih.gov/pubmed/34380018 http://dx.doi.org/10.1016/j.celrep.2021.109530 |
Ejemplares similares
-
The distinguishing NS5-M114V mutation in American Zika virus isolates has negligible impacts on virus replication and transmission potential
por: Peng, Nias Y. G., et al.
Publicado: (2022) -
An early proinflammatory transcriptional response to tau pathology is age‐specific and foreshadows reduced tau burden
por: Rasmussen, Jay, et al.
Publicado: (2021) -
Detection and Quantification of SARS-CoV-2 Receptor Binding Domain Neutralization by a Sensitive Competitive ELISA Assay
por: Shalash, Ahmed O., et al.
Publicado: (2021) -
Somatic retrotransposition in the developing rhesus macaque brain
por: Billon, Victor, et al.
Publicado: (2022) -
SARS‐CoV‐2 triggers complement activation through interactions with heparan sulfate
por: Lo, Martin W, et al.
Publicado: (2022)