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Mutations in Ehrlichia chaffeensis Genes ECH_0660 and ECH_0665 Cause Transcriptional Changes in Response to Zinc or Iron Limitation

Ehrlichia chaffeensis causes human monocytic ehrlichiosis by replicating within phagosomes of monocytes/macrophages. A function disruption mutation within the pathogen’s ECH_0660 gene, which encodes a phage head-to-tail connector protein, resulted in the rapid clearance of the pathogen in vivo, whil...

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Detalles Bibliográficos
Autores principales:	Torres-Escobar, Ascención, Juárez-Rodríguez, María D., Ganta, Roman R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316085/ https://www.ncbi.nlm.nih.gov/pubmed/33875547 http://dx.doi.org/10.1128/JB.00027-21

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