DNA damage as a mechanism of neurodegeneration in ALS and a contributor to astrocyte toxicity

Increasing evidence supports the involvement of DNA damage in several neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). Elevated levels of DNA damage are consistently observed in both sporadic and familial forms of ALS and may also play a role in Western Pacific ALS, which i...

Descripción completa

Detalles Bibliográficos
Autores principales: Kok, Jannigje Rachel, Palminha, Nelma M., Dos Santos Souza, Cleide, El-Khamisy, Sherif F., Ferraiuolo, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316199/
https://www.ncbi.nlm.nih.gov/pubmed/34173837
http://dx.doi.org/10.1007/s00018-021-03872-0

Ejemplares similares

Ejemplares similares