Cryo-EM structure of human Wntless in complex with Wnt3a

Wntless (WLS), an evolutionarily conserved multi-pass transmembrane protein, is essential for secretion of Wnt proteins. Wnt-triggered signaling pathways control many crucial life events, whereas aberrant Wnt signaling is tightly associated with many human diseases including cancers. Here, we report...

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Detalles Bibliográficos
Autores principales: Zhong, Qing, Zhao, Yanyu, Ye, Fangfei, Xiao, Zaiyu, Huang, Gaoxingyu, Xu, Meng, Zhang, Yuanyuan, Zhan, Xiechao, Sun, Ke, Wang, Zhizhi, Cheng, Shanshan, Feng, Shan, Zhao, Xiuxiu, Zhang, Jizhong, Lu, Peilong, Xu, Wenqing, Zhou, Qiang, Ma, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316347/
https://www.ncbi.nlm.nih.gov/pubmed/34315898
http://dx.doi.org/10.1038/s41467-021-24731-3

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