Chromatin remodeler ARID1A binds IRF3 to selectively induce antiviral interferon production in macrophages

Transcription factor IRF3 is critical for the induction of antiviral type I interferon (IFN-I). The epigenetic regulation of IFN-I production in antiviral innate immunity needs to be further identified. Here, we reported that epigenetic remodeler ARID1A, a critical component of the mSWI/SNF complex,...

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Detalles Bibliográficos
Autores principales: Hu, Ye, Wang, Xin, Song, Jiaying, Wu, Jiacheng, Xu, Jia, Chai, Yangyang, Ding, Yuanyuan, Wang, Bingjing, Wang, Chunmei, Zhao, Yong, Shen, Zhongyang, Xu, Xiaoqing, Cao, Xuetao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316351/
https://www.ncbi.nlm.nih.gov/pubmed/34315861
http://dx.doi.org/10.1038/s41419-021-04032-9

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