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CRISPR screening identifies CDK12 as a conservative vulnerability of prostate cancer

Androgen receptor (AR) signaling inhibitors provide limited survival benefits to patients with prostate cancer (PCa), and worse, few feasible genomic lesions restrict targeted treatment to PCa. Thus, a better understanding of the critical dependencies of PCa may enable more feasible therapeutic appr...

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Detalles Bibliográficos
Autores principales:	Lei, Hanqi, Wang, Zifeng, Jiang, Donggen, Liu, Fang, Liu, Meiling, Lei, Xinxing, Yang, Yafei, He, Bin, Yan, Min, Huang, Hai, Liu, Quentin, Pang, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316367/ https://www.ncbi.nlm.nih.gov/pubmed/34315855 http://dx.doi.org/10.1038/s41419-021-04027-6

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