Retinoblastoma from human stem cell-derived retinal organoids

Retinoblastoma is a childhood cancer of the developing retina that initiates with biallelic inactivation of the RB1 gene. Children with germline mutations in RB1 have a high likelihood of developing retinoblastoma and other malignancies later in life. Genetically engineered mouse models of retinobla...

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Detalles Bibliográficos
Autores principales: Norrie, Jackie L., Nityanandam, Anjana, Lai, Karen, Chen, Xiang, Wilson, Matthew, Stewart, Elizabeth, Griffiths, Lyra, Jin, Hongjian, Wu, Gang, Orr, Brent, Tran, Quynh, Allen, Sariah, Reilly, Colleen, Zhou, Xin, Zhang, Jiakun, Newman, Kyle, Johnson, Dianna, Brennan, Rachel, Dyer, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316454/
https://www.ncbi.nlm.nih.gov/pubmed/34315877
http://dx.doi.org/10.1038/s41467-021-24781-7

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