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Predicting involuntary hospitalization in psychiatry: A machine learning investigation

BACKGROUND: Coercion in psychiatry is a controversial issue. Identifying its predictors and their interaction using traditional statistical methods is difficult, given the large number of variables involved. The purpose of this study was to use machine-learning (ML) models to identify socio-demograp...

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Autores principales: Silva, Benedetta, Gholam, Mehdi, Golay, Philippe, Bonsack, Charles, Morandi, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316455/
https://www.ncbi.nlm.nih.gov/pubmed/34233774
http://dx.doi.org/10.1192/j.eurpsy.2021.2220
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author Silva, Benedetta
Gholam, Mehdi
Golay, Philippe
Bonsack, Charles
Morandi, Stéphane
author_facet Silva, Benedetta
Gholam, Mehdi
Golay, Philippe
Bonsack, Charles
Morandi, Stéphane
author_sort Silva, Benedetta
collection PubMed
description BACKGROUND: Coercion in psychiatry is a controversial issue. Identifying its predictors and their interaction using traditional statistical methods is difficult, given the large number of variables involved. The purpose of this study was to use machine-learning (ML) models to identify socio-demographic, clinical and procedural characteristics that predict the use of compulsory admission on a large sample of psychiatric patients. METHODS: We retrospectively analyzed the routinely collected data of all psychiatric admissions that occurred between 2013 and 2017 in the canton of Vaud, Switzerland (N = 25,584). The main predictors of involuntary hospitalization were identified using two ML algorithms: Classification and Regression Tree (CART) and Random Forests (RFs). Their predictive power was compared with that obtained through traditional logistic regression. Sensitivity analyses were also performed and missing data were imputed through multiple imputation using chain equations. RESULTS: The three models achieved similar predictive balanced accuracy, ranging between 68 and 72%. CART showed the lowest predictive power (68%) but the most parsimonious model, allowing to estimate the probability of being involuntarily admitted with only three checks: aggressive behaviors, who referred the patient to hospital and primary diagnosis. The results of CART and RFs on the imputed data were almost identical to those obtained on the original data, confirming the robustness of our models. CONCLUSIONS: Identifying predictors of coercion is essential to efficiently target the development of professional training, preventive strategies and alternative interventions. ML methodologies could offer new effective tools to achieve this goal, providing accurate but simple models that could be used in clinical practice.
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spelling pubmed-83164552021-08-06 Predicting involuntary hospitalization in psychiatry: A machine learning investigation Silva, Benedetta Gholam, Mehdi Golay, Philippe Bonsack, Charles Morandi, Stéphane Eur Psychiatry Research Article BACKGROUND: Coercion in psychiatry is a controversial issue. Identifying its predictors and their interaction using traditional statistical methods is difficult, given the large number of variables involved. The purpose of this study was to use machine-learning (ML) models to identify socio-demographic, clinical and procedural characteristics that predict the use of compulsory admission on a large sample of psychiatric patients. METHODS: We retrospectively analyzed the routinely collected data of all psychiatric admissions that occurred between 2013 and 2017 in the canton of Vaud, Switzerland (N = 25,584). The main predictors of involuntary hospitalization were identified using two ML algorithms: Classification and Regression Tree (CART) and Random Forests (RFs). Their predictive power was compared with that obtained through traditional logistic regression. Sensitivity analyses were also performed and missing data were imputed through multiple imputation using chain equations. RESULTS: The three models achieved similar predictive balanced accuracy, ranging between 68 and 72%. CART showed the lowest predictive power (68%) but the most parsimonious model, allowing to estimate the probability of being involuntarily admitted with only three checks: aggressive behaviors, who referred the patient to hospital and primary diagnosis. The results of CART and RFs on the imputed data were almost identical to those obtained on the original data, confirming the robustness of our models. CONCLUSIONS: Identifying predictors of coercion is essential to efficiently target the development of professional training, preventive strategies and alternative interventions. ML methodologies could offer new effective tools to achieve this goal, providing accurate but simple models that could be used in clinical practice. Cambridge University Press 2021-07-08 /pmc/articles/PMC8316455/ /pubmed/34233774 http://dx.doi.org/10.1192/j.eurpsy.2021.2220 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Silva, Benedetta
Gholam, Mehdi
Golay, Philippe
Bonsack, Charles
Morandi, Stéphane
Predicting involuntary hospitalization in psychiatry: A machine learning investigation
title Predicting involuntary hospitalization in psychiatry: A machine learning investigation
title_full Predicting involuntary hospitalization in psychiatry: A machine learning investigation
title_fullStr Predicting involuntary hospitalization in psychiatry: A machine learning investigation
title_full_unstemmed Predicting involuntary hospitalization in psychiatry: A machine learning investigation
title_short Predicting involuntary hospitalization in psychiatry: A machine learning investigation
title_sort predicting involuntary hospitalization in psychiatry: a machine learning investigation
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316455/
https://www.ncbi.nlm.nih.gov/pubmed/34233774
http://dx.doi.org/10.1192/j.eurpsy.2021.2220
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