Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis

Alcoholic hepatitis (AH) is associated with liver neutrophil infiltration through activated cytokine pathways leading to elevated chemokine expression. Super-enhancers are expansive regulatory elements driving augmented gene expression. Here, we explore the mechanistic role of super-enhancers linkin...

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Detalles Bibliográficos
Autores principales: Liu, Mengfei, Cao, Sheng, He, Li, Gao, Jinhang, Arab, Juan P., Cui, Huarui, Xuan, Weixia, Gao, Yandong, Sehrawat, Tejasav S., Hamdan, Feda H., Ventura-Cots, Meritxell, Argemi, Josepmaria, Pomerantz, William C. K., Johnsen, Steven A., Lee, Jeong-Heon, Gao, Fei, Ordog, Tamas, Mathurin, Philippe, Revzin, Alexander, Bataller, Ramon, Yan, Huihuang, Shah, Vijay H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316465/
https://www.ncbi.nlm.nih.gov/pubmed/34315876
http://dx.doi.org/10.1038/s41467-021-24843-w

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