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A distinct assembly pathway of the human 39S late pre-mitoribosome
Assembly of the mitoribosome is largely enigmatic and involves numerous assembly factors. Little is known about their function and the architectural transitions of the pre-ribosomal intermediates. Here, we solve cryo-EM structures of the human 39S large subunit pre-ribosomes, representing five disti...
Autores principales: | Cheng, Jingdong, Berninghausen, Otto, Beckmann, Roland |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316566/ https://www.ncbi.nlm.nih.gov/pubmed/34315873 http://dx.doi.org/10.1038/s41467-021-24818-x |
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