Diverse effects of pan-ROCK and ROCK2 inhibitors on 2 D and 3D cultured human trabecular meshwork (HTM) cells treated with TGFβ2

A pan-ROCK-inhibitor, ripasudil (Rip), and a ROCK2 inhibitor, KD025, were used To study the effects of Rho-associated coiled-coil containing protein kinase (ROCK)1 and 2 on two-dimensional (2D) and three-dimensional (3D) cultures of a TGFβ2-treated human trabecular meshwork (HTM) cells. In the prese...

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Detalles Bibliográficos
Autores principales: Watanabe, Megumi, Ida, Yosuke, Ohguro, Hiroshi, Ota, Chiaki, Hikage, Fumihito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316578/
https://www.ncbi.nlm.nih.gov/pubmed/34315994
http://dx.doi.org/10.1038/s41598-021-94791-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316578/
https://www.ncbi.nlm.nih.gov/pubmed/34315994
http://dx.doi.org/10.1038/s41598-021-94791-4

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