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Estimated Dissemination Ratio—A Practical Alternative to the Reproduction Number for Infectious Diseases

Policymakers require consistent and accessible tools to monitor the progress of an epidemic and the impact of control measures in real time. One such measure is the Estimated Dissemination Ratio (EDR), a straightforward, easily replicable, and robust measure of the trajectory of an outbreak that has...

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Autores principales: Pérez-Reche, Francisco J., Taylor, Nick, McGuigan, Chris, Conaglen, Philip, Forbes, Ken J., Strachan, Norval J. C., Honhold, Naomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316631/
https://www.ncbi.nlm.nih.gov/pubmed/34336770
http://dx.doi.org/10.3389/fpubh.2021.675065
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author Pérez-Reche, Francisco J.
Taylor, Nick
McGuigan, Chris
Conaglen, Philip
Forbes, Ken J.
Strachan, Norval J. C.
Honhold, Naomi
author_facet Pérez-Reche, Francisco J.
Taylor, Nick
McGuigan, Chris
Conaglen, Philip
Forbes, Ken J.
Strachan, Norval J. C.
Honhold, Naomi
author_sort Pérez-Reche, Francisco J.
collection PubMed
description Policymakers require consistent and accessible tools to monitor the progress of an epidemic and the impact of control measures in real time. One such measure is the Estimated Dissemination Ratio (EDR), a straightforward, easily replicable, and robust measure of the trajectory of an outbreak that has been used for many years in the control of infectious disease in livestock. It is simple to calculate and explain. Its calculation and use are discussed below together with examples from the current COVID-19 outbreak in the UK. These applications illustrate that EDR can demonstrate changes in transmission rate before they may be clear from the epidemic curve. Thus, EDR can provide an early warning that an epidemic is resuming growth, allowing earlier intervention. A conceptual comparison between EDR and the commonly used reproduction number is also provided.
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spelling pubmed-83166312021-07-29 Estimated Dissemination Ratio—A Practical Alternative to the Reproduction Number for Infectious Diseases Pérez-Reche, Francisco J. Taylor, Nick McGuigan, Chris Conaglen, Philip Forbes, Ken J. Strachan, Norval J. C. Honhold, Naomi Front Public Health Public Health Policymakers require consistent and accessible tools to monitor the progress of an epidemic and the impact of control measures in real time. One such measure is the Estimated Dissemination Ratio (EDR), a straightforward, easily replicable, and robust measure of the trajectory of an outbreak that has been used for many years in the control of infectious disease in livestock. It is simple to calculate and explain. Its calculation and use are discussed below together with examples from the current COVID-19 outbreak in the UK. These applications illustrate that EDR can demonstrate changes in transmission rate before they may be clear from the epidemic curve. Thus, EDR can provide an early warning that an epidemic is resuming growth, allowing earlier intervention. A conceptual comparison between EDR and the commonly used reproduction number is also provided. Frontiers Media S.A. 2021-07-14 /pmc/articles/PMC8316631/ /pubmed/34336770 http://dx.doi.org/10.3389/fpubh.2021.675065 Text en Copyright © 2021 Pérez-Reche, Taylor, McGuigan, Conaglen, Forbes, Strachan and Honhold. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Public Health
Pérez-Reche, Francisco J.
Taylor, Nick
McGuigan, Chris
Conaglen, Philip
Forbes, Ken J.
Strachan, Norval J. C.
Honhold, Naomi
Estimated Dissemination Ratio—A Practical Alternative to the Reproduction Number for Infectious Diseases
title Estimated Dissemination Ratio—A Practical Alternative to the Reproduction Number for Infectious Diseases
title_full Estimated Dissemination Ratio—A Practical Alternative to the Reproduction Number for Infectious Diseases
title_fullStr Estimated Dissemination Ratio—A Practical Alternative to the Reproduction Number for Infectious Diseases
title_full_unstemmed Estimated Dissemination Ratio—A Practical Alternative to the Reproduction Number for Infectious Diseases
title_short Estimated Dissemination Ratio—A Practical Alternative to the Reproduction Number for Infectious Diseases
title_sort estimated dissemination ratio—a practical alternative to the reproduction number for infectious diseases
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316631/
https://www.ncbi.nlm.nih.gov/pubmed/34336770
http://dx.doi.org/10.3389/fpubh.2021.675065
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