Eco-friendly methoximation of aromatic aldehydes and ketones using MnCl(2).4H(2)O as an easily accessible and efficient catalyst

Methoximes are important as a class of intermediates and products, among fine chemicals and specialties. The development of a new, facile and efficient method for their synthesis is reported. The methoximes were properly accessed from the corresponding aromatic aldehydes and ketones in good to excel...

Descripción completa

Detalles Bibliográficos
Autores principales: Ontivero, Melina C., Kaufman, Teodoro S., Cortés, Iván, Bracca, Andrea B. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316819/
https://www.ncbi.nlm.nih.gov/pubmed/34350014
http://dx.doi.org/10.1098/rsos.210142
_version_ 1783729942567059456
author Ontivero, Melina C.
Kaufman, Teodoro S.
Cortés, Iván
Bracca, Andrea B. J.
author_facet Ontivero, Melina C.
Kaufman, Teodoro S.
Cortés, Iván
Bracca, Andrea B. J.
author_sort Ontivero, Melina C.
collection PubMed
description Methoximes are important as a class of intermediates and products, among fine chemicals and specialties. The development of a new, facile and efficient method for their synthesis is reported. The methoximes were properly accessed from the corresponding aromatic aldehydes and ketones in good to excellent yields, under mild conditions, employing the inexpensive and environmentally friendly MnCl(2).4H(2)O as a catalyst (at low loading and without the addition of ligand), in EtOH at 50°C. The scope of the process was systematically assessed.
format Online
Article
Text
id pubmed-8316819
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher The Royal Society
record_format MEDLINE/PubMed
spelling pubmed-83168192021-08-03 Eco-friendly methoximation of aromatic aldehydes and ketones using MnCl(2).4H(2)O as an easily accessible and efficient catalyst Ontivero, Melina C. Kaufman, Teodoro S. Cortés, Iván Bracca, Andrea B. J. R Soc Open Sci Chemistry Methoximes are important as a class of intermediates and products, among fine chemicals and specialties. The development of a new, facile and efficient method for their synthesis is reported. The methoximes were properly accessed from the corresponding aromatic aldehydes and ketones in good to excellent yields, under mild conditions, employing the inexpensive and environmentally friendly MnCl(2).4H(2)O as a catalyst (at low loading and without the addition of ligand), in EtOH at 50°C. The scope of the process was systematically assessed. The Royal Society 2021-07-28 /pmc/articles/PMC8316819/ /pubmed/34350014 http://dx.doi.org/10.1098/rsos.210142 Text en © 2021 The Authors. https://creativecommons.org/licenses/by/4.0/Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, provided the original author and source are credited.
spellingShingle Chemistry
Ontivero, Melina C.
Kaufman, Teodoro S.
Cortés, Iván
Bracca, Andrea B. J.
Eco-friendly methoximation of aromatic aldehydes and ketones using MnCl(2).4H(2)O as an easily accessible and efficient catalyst
title Eco-friendly methoximation of aromatic aldehydes and ketones using MnCl(2).4H(2)O as an easily accessible and efficient catalyst
title_full Eco-friendly methoximation of aromatic aldehydes and ketones using MnCl(2).4H(2)O as an easily accessible and efficient catalyst
title_fullStr Eco-friendly methoximation of aromatic aldehydes and ketones using MnCl(2).4H(2)O as an easily accessible and efficient catalyst
title_full_unstemmed Eco-friendly methoximation of aromatic aldehydes and ketones using MnCl(2).4H(2)O as an easily accessible and efficient catalyst
title_short Eco-friendly methoximation of aromatic aldehydes and ketones using MnCl(2).4H(2)O as an easily accessible and efficient catalyst
title_sort eco-friendly methoximation of aromatic aldehydes and ketones using mncl(2).4h(2)o as an easily accessible and efficient catalyst
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316819/
https://www.ncbi.nlm.nih.gov/pubmed/34350014
http://dx.doi.org/10.1098/rsos.210142
work_keys_str_mv AT ontiveromelinac ecofriendlymethoximationofaromaticaldehydesandketonesusingmncl24h2oasaneasilyaccessibleandefficientcatalyst
AT kaufmanteodoros ecofriendlymethoximationofaromaticaldehydesandketonesusingmncl24h2oasaneasilyaccessibleandefficientcatalyst
AT cortesivan ecofriendlymethoximationofaromaticaldehydesandketonesusingmncl24h2oasaneasilyaccessibleandefficientcatalyst
AT braccaandreabj ecofriendlymethoximationofaromaticaldehydesandketonesusingmncl24h2oasaneasilyaccessibleandefficientcatalyst

Ejemplares similares