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Pancreatic cancer: A review of epidemiology, trend, and risk factors

Despite rapid advances in modern medical technology and significant improvements in survival rates of many cancers, pancreatic cancer is still a highly lethal gastrointestinal cancer with a low 5-year survival rate and difficulty in early detection. At present, the incidence and mortality of pancrea...

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Autores principales: Hu, Jian-Xiong, Zhao, Cheng-Fei, Chen, Wen-Biao, Liu, Qi-Cai, Li, Qu-Wen, Lin, Yan-Ya, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316912/
https://www.ncbi.nlm.nih.gov/pubmed/34366606
http://dx.doi.org/10.3748/wjg.v27.i27.4298
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author Hu, Jian-Xiong
Zhao, Cheng-Fei
Chen, Wen-Biao
Liu, Qi-Cai
Li, Qu-Wen
Lin, Yan-Ya
Gao, Feng
author_facet Hu, Jian-Xiong
Zhao, Cheng-Fei
Chen, Wen-Biao
Liu, Qi-Cai
Li, Qu-Wen
Lin, Yan-Ya
Gao, Feng
author_sort Hu, Jian-Xiong
collection PubMed
description Despite rapid advances in modern medical technology and significant improvements in survival rates of many cancers, pancreatic cancer is still a highly lethal gastrointestinal cancer with a low 5-year survival rate and difficulty in early detection. At present, the incidence and mortality of pancreatic cancer are increasing year by year worldwide, no matter in the United States, Europe, Japan, or China. Globally, the incidence of pancreatic cancer is projected to increase to 18.6 per 100000 in 2050, with the average annual growth of 1.1%, meaning that pancreatic cancer will pose a significant public health burden. Due to the special anatomical location of the pancreas, the development of pancreatic cancer is usually diagnosed at a late stage with obvious clinical symptoms. Therefore, a comprehensive understanding of the risk factors for pancreatic cancer is of great clinical significance for effective prevention of pancreatic cancer. In this paper, the epidemiological characteristics, developmental trends, and risk factors of pancreatic cancer are reviewed and analyzed in detail.
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spelling pubmed-83169122021-08-05 Pancreatic cancer: A review of epidemiology, trend, and risk factors Hu, Jian-Xiong Zhao, Cheng-Fei Chen, Wen-Biao Liu, Qi-Cai Li, Qu-Wen Lin, Yan-Ya Gao, Feng World J Gastroenterol Review Despite rapid advances in modern medical technology and significant improvements in survival rates of many cancers, pancreatic cancer is still a highly lethal gastrointestinal cancer with a low 5-year survival rate and difficulty in early detection. At present, the incidence and mortality of pancreatic cancer are increasing year by year worldwide, no matter in the United States, Europe, Japan, or China. Globally, the incidence of pancreatic cancer is projected to increase to 18.6 per 100000 in 2050, with the average annual growth of 1.1%, meaning that pancreatic cancer will pose a significant public health burden. Due to the special anatomical location of the pancreas, the development of pancreatic cancer is usually diagnosed at a late stage with obvious clinical symptoms. Therefore, a comprehensive understanding of the risk factors for pancreatic cancer is of great clinical significance for effective prevention of pancreatic cancer. In this paper, the epidemiological characteristics, developmental trends, and risk factors of pancreatic cancer are reviewed and analyzed in detail. Baishideng Publishing Group Inc 2021-07-21 2021-07-21 /pmc/articles/PMC8316912/ /pubmed/34366606 http://dx.doi.org/10.3748/wjg.v27.i27.4298 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Review
Hu, Jian-Xiong
Zhao, Cheng-Fei
Chen, Wen-Biao
Liu, Qi-Cai
Li, Qu-Wen
Lin, Yan-Ya
Gao, Feng
Pancreatic cancer: A review of epidemiology, trend, and risk factors
title Pancreatic cancer: A review of epidemiology, trend, and risk factors
title_full Pancreatic cancer: A review of epidemiology, trend, and risk factors
title_fullStr Pancreatic cancer: A review of epidemiology, trend, and risk factors
title_full_unstemmed Pancreatic cancer: A review of epidemiology, trend, and risk factors
title_short Pancreatic cancer: A review of epidemiology, trend, and risk factors
title_sort pancreatic cancer: a review of epidemiology, trend, and risk factors
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316912/
https://www.ncbi.nlm.nih.gov/pubmed/34366606
http://dx.doi.org/10.3748/wjg.v27.i27.4298
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