Study protocol for a multicentre, open-label, single-arm phase I/II trial to evaluate the safety and efficacy of ripasudil 0.4% eye drops for retinopathy of prematurity

INTRODUCTION: Retinopathy of prematurity (ROP) is a vascular proliferative disorder that occurs in preterm infants. Existing treatments are only indicated in severe ROP cases due to the high invasiveness and the potential risk of irreversible side effects. We previously elucidated that ripasudil, a...

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Detalles Bibliográficos
Autores principales: Arima, Mitsuru, Inoue, Hirosuke, Nakao, Shintaro, Misumi, Akiko, Suzuki, Maya, Matsushita, Itsuka, Araki, Shunsuke, Yamashiro, Chiemi, Takahashi, Kazumasa, Ochiai, Masayuki, Yoshida, Noriko, Hirose, Masayuki, Kishimoto, Junji, Todaka, Koji, Hasegawa, Shunji, Kimura, Kazuhiro, Kusuhara, Koichi, Kondo, Hiroyuki, Ohga, Shouichi, Sonoda, Koh-Hei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Ophthalmology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317081/
https://www.ncbi.nlm.nih.gov/pubmed/34315793
http://dx.doi.org/10.1136/bmjopen-2020-047003

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