Complete Response With Immunotherapy: A Case of Metastatic Bladder Cancer

Bladder cancer is the most common urinary tract malignancy. Platinum-based chemotherapy is the first line of treatment in locally advanced or metastatic bladder cancer. Immunotherapy has become a novel therapy option in a broad variety of malignancies including bladder cancer. Immunotherapy is appro...

Descripción completa

Detalles Bibliográficos
Autores principales: Singh, Balraj, Kaur, Parminder, Gupta, Sachin, Guragai, Nirmal, Maroules, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317233/
https://www.ncbi.nlm.nih.gov/pubmed/34308703
http://dx.doi.org/10.1177/23247096211035603
_version_ 1783730031083651072
author Singh, Balraj
Kaur, Parminder
Gupta, Sachin
Guragai, Nirmal
Maroules, Michael
author_facet Singh, Balraj
Kaur, Parminder
Gupta, Sachin
Guragai, Nirmal
Maroules, Michael
author_sort Singh, Balraj
collection PubMed
description Bladder cancer is the most common urinary tract malignancy. Platinum-based chemotherapy is the first line of treatment in locally advanced or metastatic bladder cancer. Immunotherapy has become a novel therapy option in a broad variety of malignancies including bladder cancer. Immunotherapy is approved as first line of treatment in patients who are ineligible for platinum-based chemotherapy and second-line treatment for metastatic urothelial cancer who progressed after platinum-based treatments. We present the case of an 83-year-old female with metastatic bladder cancer who was chemotherapy ineligible and had complete response with immune checkpoint inhibitor pembrolizumab.
format Online
Article
Text
id pubmed-8317233
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher SAGE Publications
record_format MEDLINE/PubMed
spelling pubmed-83172332021-08-06 Complete Response With Immunotherapy: A Case of Metastatic Bladder Cancer Singh, Balraj Kaur, Parminder Gupta, Sachin Guragai, Nirmal Maroules, Michael J Investig Med High Impact Case Rep Case Report Bladder cancer is the most common urinary tract malignancy. Platinum-based chemotherapy is the first line of treatment in locally advanced or metastatic bladder cancer. Immunotherapy has become a novel therapy option in a broad variety of malignancies including bladder cancer. Immunotherapy is approved as first line of treatment in patients who are ineligible for platinum-based chemotherapy and second-line treatment for metastatic urothelial cancer who progressed after platinum-based treatments. We present the case of an 83-year-old female with metastatic bladder cancer who was chemotherapy ineligible and had complete response with immune checkpoint inhibitor pembrolizumab. SAGE Publications 2021-07-26 /pmc/articles/PMC8317233/ /pubmed/34308703 http://dx.doi.org/10.1177/23247096211035603 Text en © 2021 American Federation for Medical Research https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Singh, Balraj
Kaur, Parminder
Gupta, Sachin
Guragai, Nirmal
Maroules, Michael
Complete Response With Immunotherapy: A Case of Metastatic Bladder Cancer
title Complete Response With Immunotherapy: A Case of Metastatic Bladder Cancer
title_full Complete Response With Immunotherapy: A Case of Metastatic Bladder Cancer
title_fullStr Complete Response With Immunotherapy: A Case of Metastatic Bladder Cancer
title_full_unstemmed Complete Response With Immunotherapy: A Case of Metastatic Bladder Cancer
title_short Complete Response With Immunotherapy: A Case of Metastatic Bladder Cancer
title_sort complete response with immunotherapy: a case of metastatic bladder cancer
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317233/
https://www.ncbi.nlm.nih.gov/pubmed/34308703
http://dx.doi.org/10.1177/23247096211035603
work_keys_str_mv AT singhbalraj completeresponsewithimmunotherapyacaseofmetastaticbladdercancer
AT kaurparminder completeresponsewithimmunotherapyacaseofmetastaticbladdercancer
AT guptasachin completeresponsewithimmunotherapyacaseofmetastaticbladdercancer
AT guragainirmal completeresponsewithimmunotherapyacaseofmetastaticbladdercancer
AT maroulesmichael completeresponsewithimmunotherapyacaseofmetastaticbladdercancer

Ejemplares similares