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The protective mechanism of SIRT1 on cartilage through regulation of LEF-1
BACKGROUND: Osteoarthritis (OA) is a chronic degenerative disease that suppresses middle-aged and older people worldwide. Silent information regulator 1(SIRT-1) is associated with several age-related diseases, such as cardiovascular diseases, neurodegenerative diseases and tumors, etc. The protectiv...
Autores principales: | Hu, Xueyu, Feng, Gangning, Meng, Zhiqiang, Ma, Long, Jin, Qunhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317295/ https://www.ncbi.nlm.nih.gov/pubmed/34315467 http://dx.doi.org/10.1186/s12891-021-04516-x |
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