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Fine-tuning the expression of pathway gene in yeast using a regulatory library formed by fusing a synthetic minimal promoter with different Kozak variants
BACKGROUND: Tailoring gene expression to balance metabolic fluxes is critical for the overproduction of metabolites in yeast hosts, and its implementation requires coordinated regulation at both transcriptional and translational levels. Although synthetic minimal yeast promoters have shown many adva...
Autores principales: | Xu, Liping, Liu, Pingping, Dai, Zhubo, Fan, Feiyu, Zhang, Xueli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317321/ https://www.ncbi.nlm.nih.gov/pubmed/34320991 http://dx.doi.org/10.1186/s12934-021-01641-z |
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