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MUREN: a robust and multi-reference approach of RNA-seq transcript normalization

BACKGROUND: Normalization of RNA-seq data aims at identifying biological expression differentiation between samples by removing the effects of unwanted confounding factors. Explicitly or implicitly, the justification of normalization requires a set of housekeeping genes. However, the existence of ho...

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Detalles Bibliográficos
Autores principales: Feng, Yance, Li, Lei M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317383/
https://www.ncbi.nlm.nih.gov/pubmed/34320923
http://dx.doi.org/10.1186/s12859-021-04288-0