Extracellular vesicles derived from LPS-preconditioned human synovial mesenchymal stem cells inhibit extracellular matrix degradation and prevent osteoarthritis of the knee in a mouse model

BACKGROUND: Previous studies report that lipopolysaccharide (LPS)-preconditioned mesenchymal stem cells have enhanced trophic support and improved regenerative and repair properties. Extracellular vesicles secreted by synovial mesenchymal stem cells (EVs) can reduce cartilage damage caused by osteoa...

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Detalles Bibliográficos
Autores principales: Duan, Ao, Shen, Kai, Li, Beichen, Li, Cong, Zhou, Hao, Kong, Renyi, Shao, Yuqi, Qin, Jian, Yuan, Tangbo, Ji, Juan, Guo, Wei, Wang, Xipeng, Xue, Tengfei, Li, Lei, Huang, Xinxin, Sun, Yuqin, Cai, Zhenyu, Liu, Wei, Liu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317426/
https://www.ncbi.nlm.nih.gov/pubmed/34321073
http://dx.doi.org/10.1186/s13287-021-02507-2

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