Binding of a pyrimidine RNA base-mimic to SARS-CoV-2 nonstructural protein 9

The coronaviral nonstructural protein 9 (Nsp9) is essential for viral replication; it is the primary substrate of Nsp12’s pseudokinase domain within the viral replication transcription complex, an association that also recruits other components during different stages of RNA reproduction. In the unm...

Descripción completa

Detalles Bibliográficos
Autores principales: Littler, Dene R., Mohanty, Biswaranjan, Lowery, Shea A., Colson, Rhys N., Gully, Benjamin S., Perlman, Stanley, Scanlon, Martin J., Rossjohn, Jamie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317483/
https://www.ncbi.nlm.nih.gov/pubmed/34331944
http://dx.doi.org/10.1016/j.jbc.2021.101018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317483/
https://www.ncbi.nlm.nih.gov/pubmed/34331944
http://dx.doi.org/10.1016/j.jbc.2021.101018

Ejemplares similares