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Binding of a pyrimidine RNA base-mimic to SARS-CoV-2 nonstructural protein 9
The coronaviral nonstructural protein 9 (Nsp9) is essential for viral replication; it is the primary substrate of Nsp12’s pseudokinase domain within the viral replication transcription complex, an association that also recruits other components during different stages of RNA reproduction. In the unm...
Autores principales: | Littler, Dene R., Mohanty, Biswaranjan, Lowery, Shea A., Colson, Rhys N., Gully, Benjamin S., Perlman, Stanley, Scanlon, Martin J., Rossjohn, Jamie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317483/ https://www.ncbi.nlm.nih.gov/pubmed/34331944 http://dx.doi.org/10.1016/j.jbc.2021.101018 |
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